Georgetown District extended from the North Carolina line to the Santee River. Charleston District lay between the Santee and the Combahee Rivers. Beaufort District sat between the Combahee and the Savannah Rivers. Northwest of Georgetown was the Cheraws District, bounded on the west by Lynches River; west of the Cheraws was the large district of Camden, bounded on the west by the river system of the Santee, Congaree, and Broad; south and west of Camden, two more large districts extended to the Savannah River—Orangeburg District to the south, and Ninety-Six District to the north.
(Source: South Carolina Department of Archives and History, http://www.state.sc.us/scdah/guide/countymap2.htm)